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{{STRUCTURE_4ddq|  PDB=4ddq  |  SCENE=  }}
===Structural plasticity of the Bacillus subtilis GyrA homodimer===
{{ABSTRACT_PUBMED_23602808}}


==Function==
==Structural plasticity of the Bacillus subtilis GyrA homodimer==
[[http://www.uniprot.org/uniprot/GYRA_BACSU GYRA_BACSU]] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity).  
<StructureSection load='4ddq' size='340' side='right'caption='[[4ddq]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ddq]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DDQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DDQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ddq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ddq OCA], [https://pdbe.org/4ddq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ddq RCSB], [https://www.ebi.ac.uk/pdbsum/4ddq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ddq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GYRA_BACSU GYRA_BACSU] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity).


==About this Structure==
==See Also==
[[4ddq]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DDQ OCA].
*[[Gyrase 3D Structures|Gyrase 3D Structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:023602808</ref><references group="xtra"/><references/>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Klostermeier, D.]]
[[Category: Large Structures]]
[[Category: Rudolph, M G.]]
[[Category: Klostermeier D]]
[[Category: C-gate]]
[[Category: Rudolph MG]]
[[Category: Dna-gate]]
[[Category: Gyrase]]
[[Category: Isomerase]]
[[Category: Supercoiling]]
[[Category: Topoisomerase ii]]
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