4fk2: Difference between revisions

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{{STRUCTURE_4fk2|  PDB=4fk2  |  SCENE=  }}
===RB69 DNA polymerase ternary complex with dTTP/dG===
{{ABSTRACT_PUBMED_23214497}}


==Function==
==RB69 DNA polymerase ternary complex with dTTP/dG==
[[http://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69]] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.
<StructureSection load='4fk2' size='340' side='right'caption='[[4fk2]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4fk2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_RB69 Escherichia phage RB69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FK2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FK2 FirstGlance]. <br>
[[4fk2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FK2 OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.98&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DOC:2,3-DIDEOXYCYTIDINE-5-MONOPHOSPHATE'>DOC</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fk2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fk2 OCA], [https://pdbe.org/4fk2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fk2 RCSB], [https://www.ebi.ac.uk/pdbsum/4fk2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fk2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.


==See Also==
==See Also==
*[[DNA polymerase|DNA polymerase]]
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:023214497</ref><references group="xtra"/><references/>
[[Category: Escherichia phage RB69]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Large Structures]]
[[Category: Enterobacteria phage rb69]]
[[Category: Konigsberg WH]]
[[Category: Konigsberg, W H.]]
[[Category: Wang J]]
[[Category: Wang, J.]]
[[Category: Xia S]]
[[Category: Xia, S.]]
[[Category: Dttp/dg]]
[[Category: Quadruple]]
[[Category: Rb69]]
[[Category: Rb69 pol]]
[[Category: Transferase-dna complex]]

Latest revision as of 11:17, 1 March 2024

RB69 DNA polymerase ternary complex with dTTP/dG

4fk2, resolution 1.98Å

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