4ksc: Difference between revisions
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== | ==Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain== | ||
[[ | <StructureSection load='4ksc' size='340' side='right'caption='[[4ksc]], [[Resolution|resolution]] 4.00Å' scene=''> | ||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[4ksc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KSC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KSC FirstGlance]. <br> | ||
[[4ksc]] is a 1 chain structure with sequence from [ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ksc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ksc OCA], [https://pdbe.org/4ksc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ksc RCSB], [https://www.ebi.ac.uk/pdbsum/4ksc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ksc ProSAT]</span></td></tr> | |||
== | </table> | ||
< | == Function == | ||
[https://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Caya A]] | |||
[[Category: Caya | [[Category: Chang G]] | ||
[[Category: Chang | [[Category: Cregger C]] | ||
[[Category: Cregger | [[Category: Doshi R]] | ||
[[Category: Doshi | [[Category: Falson P]] | ||
[[Category: Falson | [[Category: Govaerts C]] | ||
[[Category: Govaerts | [[Category: Grimard V]] | ||
[[Category: Grimard | [[Category: Lee C-W]] | ||
[[Category: Lee | [[Category: Martinez L]] | ||
[[Category: Martinez | [[Category: Pardon E]] | ||
[[Category: Pardon | [[Category: Steyaert J]] | ||
[[Category: Steyaert | [[Category: Swartz DJ]] | ||
[[Category: Swartz | [[Category: Szewczyk P]] | ||
[[Category: Szewczyk | [[Category: Urbatsch I]] | ||
[[Category: Urbatsch | [[Category: Villaluz M]] | ||
[[Category: Villaluz | [[Category: Ward A]] | ||
[[Category: Ward | |||
Latest revision as of 12:15, 1 March 2024
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
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