2jan: Difference between revisions

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[[Image:2jan.jpg|left|200px]]<br /><applet load="2jan" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2jan, resolution 2.90&Aring;" />
'''TYROSYL-TRNA SYNTHETASE FROM MYCOBACTERIUM TUBERCULOSIS IN UNLIGANDED STATE'''<br />


==About this Structure==
==TYROSYL-TRNA SYNTHETASE FROM MYCOBACTERIUM TUBERCULOSIS IN UNLIGANDED STATE==
2JAN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Active as [http://en.wikipedia.org/wiki/Tyrosine--tRNA_ligase Tyrosine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.1 6.1.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JAN OCA].  
<StructureSection load='2jan' size='340' side='right'caption='[[2jan]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
[[Category: Mycobacterium tuberculosis]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2jan]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JAN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JAN FirstGlance]. <br>
[[Category: Tyrosine--tRNA ligase]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
[[Category: Bartunik, H D.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jan OCA], [https://pdbe.org/2jan PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jan RCSB], [https://www.ebi.ac.uk/pdbsum/2jan PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jan ProSAT]</span></td></tr>
[[Category: Bourenkov, G P.]]
</table>
[[Category: Hartmann, M D.]]
== Function ==
[[Category: Shkolnaya, L A.]]
[https://www.uniprot.org/uniprot/SYY_MYCTU SYY_MYCTU] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity).
[[Category: Strizhov, N I.]]
== Evolutionary Conservation ==
[[Category: aminoacyl-trna synthetase]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: aminoacylation]]
Check<jmol>
[[Category: atp-binding]]
  <jmolCheckbox>
[[Category: ligase]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ja/2jan_consurf.spt"</scriptWhenChecked>
[[Category: nucleotide-binding]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: protein biosynthesis]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: rna-binding]]
  </jmolCheckbox>
[[Category: trna]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jan ConSurf].
[[Category: tyrosine]]
<div style="clear:both"></div>
[[Category: tyrrs]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:01:08 2008''
==See Also==
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Bartunik HD]]
[[Category: Bourenkov GP]]
[[Category: Hartmann MD]]
[[Category: Shkolnaya LA]]
[[Category: Strizhov NI]]
Retrieved from "https://proteopedia.org/2jan"