3w0m: Difference between revisions
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== | ==Crystal structure of a thermostable mutant of aminoglycoside phosphotransferase APH(4)-Ia, apo form== | ||
[[ | <StructureSection load='3w0m' size='340' side='right'caption='[[3w0m]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[3w0m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W0M FirstGlance]. <br> | ||
[[3w0m]] is a 1 chain structure with sequence from [ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w0m OCA], [https://pdbe.org/3w0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w0m RCSB], [https://www.ebi.ac.uk/pdbsum/3w0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w0m ProSAT]</span></td></tr> | ||
< | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/KHYB_ECOLX KHYB_ECOLX] The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation. Only phosphorylates hygromycin and closely related compounds such as demethyl analogs and destomycin. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Fukano | [[Category: Fukano K]] | ||
[[Category: Hoshino | [[Category: Hoshino T]] | ||
[[Category: Iino | [[Category: Iino D]] | ||
[[Category: Nakamura | [[Category: Nakamura A]] | ||
[[Category: Ohsawa | [[Category: Ohsawa K]] | ||
[[Category: Sasaki | [[Category: Sasaki Y]] | ||
[[Category: Takakura | [[Category: Takakura Y]] | ||
[[Category: Yajima | [[Category: Yajima S]] | ||
Latest revision as of 08:43, 20 March 2024
Crystal structure of a thermostable mutant of aminoglycoside phosphotransferase APH(4)-Ia, apo form
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