4lhr: Difference between revisions
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== | ==Crystal structure of a deoxyuridine 5'-triphosphate nucleotidohydrolase from Burkholderia thailandensis== | ||
[[http://www.uniprot.org/uniprot/DUT_BURTA DUT_BURTA | <StructureSection load='4lhr' size='340' side='right'caption='[[4lhr]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4lhr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_thailandensis_E264 Burkholderia thailandensis E264]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LHR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LHR FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lhr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lhr OCA], [https://pdbe.org/4lhr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lhr RCSB], [https://www.ebi.ac.uk/pdbsum/4lhr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lhr ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DUT_BURTA DUT_BURTA] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity). | |||
== | ==See Also== | ||
[[ | *[[DUTPase 3D structures|DUTPase 3D structures]] | ||
[[Category: Burkholderia thailandensis | __TOC__ | ||
</StructureSection> | |||
[[Category: Burkholderia thailandensis E264]] | |||
[[Category: Large Structures]] | |||
[[Category: | |||
Latest revision as of 16:19, 20 September 2023
Crystal structure of a deoxyuridine 5'-triphosphate nucleotidohydrolase from Burkholderia thailandensis
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