4c0l: Difference between revisions

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New page: '''Unreleased structure''' The entry 4c0l is ON HOLD Authors: Klosowiak, J.L., Focia, P.J., Wawrzak, Z., Chakravarthy, S., Landahl, E.C., Freymann, D.M., Rice, S.E. Description: Crysta...
 
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'''Unreleased structure'''


The entry 4c0l is ON HOLD
==Crystal structure of Drosophila Miro EF hand and cGTPase domains bound to one magnesium ion and Mg:GDP (MgGDP-MiroS)==
<StructureSection load='4c0l' size='340' side='right'caption='[[4c0l]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4c0l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C0L FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=HSE:L-HOMOSERINE'>HSE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c0l OCA], [https://pdbe.org/4c0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c0l RCSB], [https://www.ebi.ac.uk/pdbsum/4c0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c0l ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MIRO_DROME MIRO_DROME] Mitochondrial GTPase involved in mitochondrial trafficking. Milt and Miro form an essential protein complex that links Khc to mitochondria for light chain-independent, anterograde transport of mitochondria. Required for axonal transport to synapses within nerve terminals. Required presynaptically but not postsynaptically at neuromuscular junctions (NMJs).<ref>PMID:16055062</ref> <ref>PMID:16717129</ref>


Authors: Klosowiak, J.L., Focia, P.J., Wawrzak, Z., Chakravarthy, S., Landahl, E.C., Freymann, D.M., Rice, S.E.
==See Also==
 
*[[Rho GTPase 3D structures|Rho GTPase 3D structures]]
Description: Crystal structure of the outer mitochondrial membrane protein Miro bound to magnesium ion and guanosine diphosphate
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Chakravarthy S]]
[[Category: Focia PJ]]
[[Category: Freymann DM]]
[[Category: Klosowiak JL]]
[[Category: Landahl EC]]
[[Category: Rice SE]]
[[Category: Wawrzak Z]]
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