4lun: Difference between revisions
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==Structure of the N-terminal mIF4G domain from S. cerevisiae Upf2, a protein involved in the degradation of mRNAs containing premature stop codons== | |||
<StructureSection load='4lun' size='340' side='right'caption='[[4lun]], [[Resolution|resolution]] 1.64Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4lun]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LUN FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.641Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lun OCA], [https://pdbe.org/4lun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lun RCSB], [https://www.ebi.ac.uk/pdbsum/4lun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lun ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NMD2_YEAST NMD2_YEAST] Involved in nonsense-mediated decay of mRNAs containing premature stop codons. It interacts, via its C-terminus, with NAM7/UPF1. Could be involved in determining the efficiency of translational termination or reinitiation or factors involved in the initial assembly of an initiation- and termination-competent mRNP. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae S288C]] | |||
[[Category: Courreux PD]] | |||
[[Category: Fourati Z]] | |||
[[Category: Graille M]] | |||
[[Category: He F]] | |||
[[Category: Jacobson A]] | |||
[[Category: Kervestin S]] | |||
[[Category: Millan C]] | |||
[[Category: Roy B]] | |||
[[Category: Uson I]] | |||
[[Category: Van Tilbeurgh H]] | |||
Latest revision as of 12:21, 1 March 2024
Structure of the N-terminal mIF4G domain from S. cerevisiae Upf2, a protein involved in the degradation of mRNAs containing premature stop codons
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