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[[Image:2jqv.jpg|left|200px]]<br /><applet load="2jqv" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2jqv" />
'''Solution structure At3g28950.1 from Arabidopsis thaliana'''<br />


==About this Structure==
==Solution structure At3g28950.1 from Arabidopsis thaliana==
2JQV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JQV OCA].  
<StructureSection load='2jqv' size='340' side='right'caption='[[2jqv]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2jqv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JQV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JQV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jqv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jqv OCA], [https://pdbe.org/2jqv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jqv RCSB], [https://www.ebi.ac.uk/pdbsum/2jqv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jqv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AIG2C_ARATH AIG2C_ARATH] Putative gamma-glutamylcyclotransferase.[UniProtKB:O75223]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jq/2jqv_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jqv ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
We determined the solution structure of At3g28950 from A. thaliana, a homolog of At5g39720, whose structure we solved earlier. The secondary structure of the 165-aa protein consists of a 5-strand antiparallel beta-barrel domain flanked by two alpha-helices and a 2-strand beta-sheet; an additional free C-terminal alpha-helix extends into solution. Bioinformatic searches and analyses suggest that members of this growing set of structurally related proteins have been recruited to serve a wide variety of functions ranging from gamma-glutamyl cyclotransferase activity to participation in plant responses to chemical and biotic stimuli. Expression of a human homolog is elevated in bladder cancer tissues. Expression patterns for At3g28950 and its Arabidopsis paralogs suggest that each one evolved a different physiological role. The At3g28950 structure was solved as part of a structural genomics effort, and the results demonstrate how such a project can further understanding of genome evolution in addition to sequence-structure and structure-function relationships. Proteins 2008. (c) 2008 Wiley-Liss, Inc.
 
Solution structure of At3g28950 from Arabidopsis thaliana.,de la Cruz NB, Peterson FC, Volkman BF Proteins. 2008 May 1;71(2):546-51. PMID:18214976<ref>PMID:18214976</ref>
 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2jqv" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
[[Category: Peterson FC]]
[[Category: Cruz, N B.de la.]]
[[Category: Volkman BF]]
[[Category: Peterson, F C.]]
[[Category: De la Cruz NB]]
[[Category: Volkman, B F.]]
[[Category: at3g28950 1]]
[[Category: center for eukaryotic structural genomics]]
[[Category: cesg]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomics]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:05:16 2008''

Latest revision as of 10:11, 20 December 2023

Solution structure At3g28950.1 from Arabidopsis thaliana

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