2jx1: Difference between revisions

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[[Image:2jx1.gif|left|200px]]<br /><applet load="2jx1" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2jx1" />
'''Structure of the fifth zinc finger of Myelin Transcription Factor 1 in complex with RARE DNA'''<br />


==About this Structure==
==Structure of the fifth zinc finger of Myelin Transcription Factor 1 in complex with RARE DNA==
2JX1 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JX1 OCA].  
<StructureSection load='2jx1' size='340' side='right'caption='[[2jx1]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2jx1]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JX1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JX1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jx1 OCA], [https://pdbe.org/2jx1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jx1 RCSB], [https://www.ebi.ac.uk/pdbsum/2jx1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jx1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MYT1_MOUSE MYT1_MOUSE] Binds to the promoter regions of proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendrogalia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription (By similarity).<ref>PMID:9373037</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jx/2jx1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jx1 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Protein complex]]
[[Category: Gamsjaeger R]]
[[Category: Gamsjaeger, R.]]
[[Category: Kobus FJ]]
[[Category: Kobus, F J.]]
[[Category: Kwan AH]]
[[Category: Kwan, A H.]]
[[Category: Lehtomaki E]]
[[Category: Lehtomaki, E.]]
[[Category: Lowry JA]]
[[Category: Lowry, J A.]]
[[Category: Mackay JP]]
[[Category: Mackay, J P.]]
[[Category: Matthews JM]]
[[Category: Matthews, J M.]]
[[Category: Swanton MK]]
[[Category: Swanton, M K.]]
[[Category: protein-dna complex]]
[[Category: transcription/dna complex]]
 
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Retrieved from "https://proteopedia.org/2jx1"