4m55: Difference between revisions
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== | ==Crystal structure of Human UDP-xylose synthase R236H substitution== | ||
[[ | <StructureSection load='4m55' size='340' side='right'caption='[[4m55]], [[Resolution|resolution]] 2.86Å' scene=''> | ||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[4m55]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M55 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M55 FirstGlance]. <br> | ||
[[4m55]] is a 6 chain structure with sequence from [ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.86Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m55 OCA], [https://pdbe.org/4m55 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m55 RCSB], [https://www.ebi.ac.uk/pdbsum/4m55 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m55 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/UXS1_HUMAN UXS1_HUMAN] Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Polizzi | [[Category: Polizzi SJ]] | ||
[[Category: Walsh | [[Category: Walsh Jr RM]] | ||
[[Category: Wood | [[Category: Wood ZA]] | ||
Latest revision as of 12:24, 1 March 2024
Crystal structure of Human UDP-xylose synthase R236H substitution
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