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{{STRUCTURE_4ha9|  PDB=4ha9  |  SCENE=  }}
===Structural insights into the reduction mechanism of Saccharomyces cerevisia Riboflavin Biosynthesis Reductase Rib7===
{{ABSTRACT_PUBMED_23620735}}


==Function==
==Structural insights into the reduction mechanism of Saccharomyces cerevisia Riboflavin Biosynthesis Reductase Rib7==
[[http://www.uniprot.org/uniprot/RIB7_YEAST RIB7_YEAST]] Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate (Probable).
<StructureSection load='4ha9' size='340' side='right'caption='[[4ha9]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4ha9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HA9 FirstGlance]. <br>
[[4ha9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HA9 OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ha9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ha9 OCA], [https://pdbe.org/4ha9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ha9 RCSB], [https://www.ebi.ac.uk/pdbsum/4ha9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ha9 ProSAT]</span></td></tr>
<ref group="xtra">PMID:023620735</ref><references group="xtra"/><references/>
</table>
[[Category: Saccharomyces cerevisiae s288c]]
== Function ==
[[Category: Liu, Y.]]
[https://www.uniprot.org/uniprot/RIB7_YEAST RIB7_YEAST] Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate (Probable).
[[Category: Lv, Z.]]
__TOC__
[[Category: Sun, J.]]
</StructureSection>
[[Category: Nadph binding]]
[[Category: Large Structures]]
[[Category: Oxidoreductase]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Reductase]]
[[Category: Liu Y]]
[[Category: Lv Z]]
[[Category: Sun J]]