4l0r: Difference between revisions
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== | ==Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics Consortium Target HR9027A.== | ||
[[http://www.uniprot.org/uniprot/CEP57_HUMAN CEP57_HUMAN | <StructureSection load='4l0r' size='340' side='right'caption='[[4l0r]], [[Resolution|resolution]] 2.49Å' scene=''> | ||
== Structural highlights == | |||
==Function== | <table><tr><td colspan='2'>[[4l0r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L0R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L0R FirstGlance]. <br> | ||
[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.49Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l0r OCA], [https://pdbe.org/4l0r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l0r RCSB], [https://www.ebi.ac.uk/pdbsum/4l0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l0r ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/CEP57_HUMAN CEP57_HUMAN] Mosaic variegated aneuploidy syndrome. The disease is caused by mutations affecting the gene represented in this entry. | |||
== | == Function == | ||
<references | [https://www.uniprot.org/uniprot/CEP57_HUMAN CEP57_HUMAN] Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1.<ref>PMID:22321063</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Acton | [[Category: Large Structures]] | ||
[[Category: Ciccosanti | [[Category: Acton TB]] | ||
[[Category: Everett | [[Category: Ciccosanti C]] | ||
[[Category: Hunt | [[Category: Everett JK]] | ||
[[Category: Lew | [[Category: Hunt JF]] | ||
[[Category: Montelione | [[Category: Lew S]] | ||
[[Category: Montelione GT]] | |||
[[Category: Sahdev | [[Category: Sahdev S]] | ||
[[Category: Seetharaman | [[Category: Seetharaman J]] | ||
[[Category: Su | [[Category: Su M]] | ||
[[Category: Tong | [[Category: Tong L]] | ||
[[Category: Xiao | [[Category: Xiao R]] | ||
Latest revision as of 12:16, 1 March 2024
Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics Consortium Target HR9027A.
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