4mhv: Difference between revisions
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New page: '''Unreleased structure''' The entry 4mhv is ON HOLD Authors: Newman, J.A., Cooper, C.D.O., Krojer, T., Shrestha, L., Burgess-brown, N., Arrowsmith, C.H., Bountra, C., Edwards, A., Gile... |
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==Crystal structure of the PNT domain of human ETS2== | |||
<StructureSection load='4mhv' size='340' side='right'caption='[[4mhv]], [[Resolution|resolution]] 2.45Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4mhv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MHV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MHV FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mhv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mhv OCA], [https://pdbe.org/4mhv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mhv RCSB], [https://www.ebi.ac.uk/pdbsum/4mhv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mhv ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ETS2_HUMAN ETS2_HUMAN] Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.<ref>PMID:11909962</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Bountra C]] | |||
[[Category: Burgess-brown N]] | |||
[[Category: Cooper CDO]] | |||
[[Category: Edwards A]] | |||
[[Category: Gileadi O]] | |||
[[Category: Krojer T]] | |||
[[Category: Newman JA]] | |||
[[Category: Shrestha L]] | |||
Latest revision as of 12:26, 1 March 2024
Crystal structure of the PNT domain of human ETS2
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