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{{STRUCTURE_4gvi|  PDB=4gvi  |  SCENE=  }}
===Crystal structure of mutant (D248N) Salmonella typhimurium family 3 glycoside hydrolase (NagZ) in complex with GlcNAc-1,6-anhMurNAc===
{{ABSTRACT_PUBMED_23177201}}


==Function==
==Crystal structure of mutant (D248N) Salmonella typhimurium family 3 glycoside hydrolase (NagZ) in complex with GlcNAc-1,6-anhMurNAc==
[[http://www.uniprot.org/uniprot/NAGZ_SALTY NAGZ_SALTY]] Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity).  
<StructureSection load='4gvi' size='340' side='right'caption='[[4gvi]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4gvi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GVI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GVI FirstGlance]. <br>
[[4gvi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GVI OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AH0:2-(2-ACETYLAMINO-4-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCT-3-YLOXY)-PROPIONIC+ACID'>AH0</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gvi OCA], [https://pdbe.org/4gvi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gvi RCSB], [https://www.ebi.ac.uk/pdbsum/4gvi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gvi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NAGZ_SALTY NAGZ_SALTY] Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity).


==See Also==
==See Also==
*[[Beta-Hexosaminidase|Beta-Hexosaminidase]]
*[[Beta-Hexosaminidase|Beta-Hexosaminidase]]
 
*[[Beta-Hexosaminidase 3D structures|Beta-Hexosaminidase 3D structures]]
==Reference==
*[[Beta-N-acetylhexosaminidase 3D structures|Beta-N-acetylhexosaminidase 3D structures]]
<ref group="xtra">PMID:023177201</ref><references group="xtra"/><references/>
__TOC__
[[Category: Beta-N-acetylhexosaminidase]]
</StructureSection>
[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]]
[[Category: Large Structures]]
[[Category: Bacik, J P.]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
[[Category: Mark, B L.]]
[[Category: Bacik JP]]
[[Category: Hydrolase]]
[[Category: Mark BL]]
[[Category: Tim-barrel]]
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