4mmh: Difference between revisions

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New page: '''Unreleased structure''' The entry 4mmh is ON HOLD until Paper Publication Authors: Maruyama, Y., Nakamichi, Y., Mikami, B., Murata, K., Hashimoto, W. Description: Crystal structure ...
 
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'''Unreleased structure'''


The entry 4mmh is ON HOLD  until Paper Publication
==Crystal structure of heparan sulfate lyase HepC from Pedobacter heparinus==
 
<StructureSection load='4mmh' size='340' side='right'caption='[[4mmh]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
Authors: Maruyama, Y., Nakamichi, Y., Mikami, B., Murata, K., Hashimoto, W.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4mmh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pedobacter_heparinus Pedobacter heparinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MMH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MMH FirstGlance]. <br>
Description: Crystal structure of heparan sulfate lyase HepC from Pedobacter heparinus
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mmh OCA], [https://pdbe.org/4mmh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mmh RCSB], [https://www.ebi.ac.uk/pdbsum/4mmh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mmh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HEPC_PEDHD HEPC_PEDHD] Specifically cleaves heparan sulfate-rich regions of acidic polysaccharides. Does not act on N,O-desulfated glucosamine or N-acetyl-O-sulfated glucosamine linkages. Functions in cleaving metazoan heparan sulfate and providing carbon, nitrogen and sulfate sources for microorganisms.<ref>PMID:8702264</ref> <ref>PMID:10747789</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pedobacter heparinus]]
[[Category: Hashimoto W]]
[[Category: Maruyama Y]]
[[Category: Mikami B]]
[[Category: Murata K]]
[[Category: Nakamichi Y]]
Retrieved from "https://proteopedia.org/4mmh"