4ln7: Difference between revisions

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{{STRUCTURE_4ln7|  PDB=4ln7  |  SCENE=  }}
===5,6-bis(4-fluorophenyl)-3-hydroxy-2,5-dihydropyridin-2-one bound to influenza 2009 pH1N1 endonuclease===
{{ABSTRACT_PUBMED_23978130}}


==Function==
==5,6-bis(4-fluorophenyl)-3-hydroxy-2,5-dihydropyridin-2-one bound to influenza 2009 pH1N1 endonuclease==
[[http://www.uniprot.org/uniprot/F0TRT1_9INFA F0TRT1_9INFA]] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication (By similarity).[SAAS:SAAS001009_004_020464]  
<StructureSection load='4ln7' size='340' side='right'caption='[[4ln7]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4ln7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/Lima/WRAIR1695P/2009(H1N1)) Influenza A virus (A/Lima/WRAIR1695P/2009(H1N1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LN7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LN7 FirstGlance]. <br>
[[4ln7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus_(a/lima/wrair1695p/2009(h1n1)) Influenza a virus (a/lima/wrair1695p/2009(h1n1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LN7 OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1ZQ:5,6-BIS(4-FLUOROPHENYL)PYRIDINE-2,3-DIOL'>1ZQ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ln7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ln7 OCA], [https://pdbe.org/4ln7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ln7 RCSB], [https://www.ebi.ac.uk/pdbsum/4ln7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ln7 ProSAT]</span></td></tr>
<ref group="xtra">PMID:023978130</ref><references group="xtra"/><references/>
</table>
[[Category: Arnold, E.]]
__TOC__
[[Category: Bauman, J D.]]
</StructureSection>
[[Category: Das, K.]]
[[Category: Large Structures]]
[[Category: Patel, D.]]
[[Category: Arnold E]]
[[Category: Cap-snatching]]
[[Category: Bauman JD]]
[[Category: Rna binding protein-inhibitor]]
[[Category: Das K]]
[[Category: Rna binding protein-inhibitor complex]]
[[Category: Patel D]]
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