4b44: Difference between revisions

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~~{{STRUCTURE_4b44| PDB=4b44 | SCENE= }}~~

~~===Bacterial translation initiation factor IF2 (1-363), complex with GDP at pH6.5===~~

==~~Function~~==

==Bacterial translation initiation factor IF2 (1-363), complex with GDP at pH8.0==

[[~~http://www.uniprot.org/uniprot/IF2_THET8 IF2_THET8~~]] One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).

== Structural highlights ==

==~~About this Structure~~==

<table><tr><td colspan='2'>[[4b44]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B44 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=4B44 FirstGlance].

[[4b44]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Thermus_thermophilus_hb8~~ Thermus thermophilus ~~hb8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B44 OCA].

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr>

[[~~Category~~: ~~Thermus thermophilus hb8~~]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>

[[~~Category~~: ~~Klaholz~~, ~~B P~~.]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=4b44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b44 OCA], [https://pdbe.org/4b44 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b44 RCSB], [https://www.ebi.ac.uk/pdbsum/4b44 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b44 ProSAT]</td></tr>

[[Category: ~~Simonetti, A.~~]]

</table>

[[Category: ~~Urzhumtsev, A.~~]]

== Function ==

[[Category: ~~Gtp hydrolysis mechanism~~]]

[https://www.uniprot.org/uniprot/IF2_THET8 IF2_THET8] One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).

[[Category: ~~Initiation~~]]

__TOC__

[[Category: ~~Translation~~]]

</StructureSection>

[[Category: Large Structures]]

[[Category: Thermus thermophilus HB8]]

[[Category: Klaholz BP]]

[[Category: Simonetti A]]

[[Category: Urzhumtsev A]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_4b44|  PDB=4b44  |  SCENE=  }}
-===Bacterial translation initiation factor IF2 (1-363), complex with GDP at pH6.5===
-==Function==
+==Bacterial translation initiation factor IF2 (1-363), complex with GDP at pH8.0==
-[[http://www.uniprot.org/uniprot/IF2_THET8 IF2_THET8]] One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
+<StructureSection load='4b44' size='340' side='right'caption='[[4b44]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
+== Structural highlights ==
-==About this Structure==
+<table><tr><td colspan='2'>[[4b44]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B44 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B44 FirstGlance]. <br>
-[[4b44]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B44 OCA].
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-[[Category: Thermus thermophilus hb8]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
-[[Category: Klaholz, B P.]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b44 OCA], [https://pdbe.org/4b44 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b44 RCSB], [https://www.ebi.ac.uk/pdbsum/4b44 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b44 ProSAT]</span></td></tr>
-[[Category: Simonetti, A.]]
+</table>
-[[Category: Urzhumtsev, A.]]
+== Function ==
-[[Category: Gtp hydrolysis mechanism]]
+[https://www.uniprot.org/uniprot/IF2_THET8 IF2_THET8] One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
-[[Category: Initiation]]
+__TOC__
-[[Category: Translation]]
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Thermus thermophilus HB8]]
+[[Category: Klaholz BP]]
+[[Category: Simonetti A]]
+[[Category: Urzhumtsev A]]