4luq: Difference between revisions
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== | ==Crystal structure of virulence effector Tse3 in complex with neutralizer Tsi3== | ||
[[4luq]] is a 4 chain structure with sequence from [ | <StructureSection load='4luq' size='340' side='right'caption='[[4luq]], [[Resolution|resolution]] 1.77Å' scene=''> | ||
[[ | == Structural highlights == | ||
[[ | <table><tr><td colspan='2'>[[4luq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LUQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LUQ FirstGlance]. <br> | ||
[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77Å</td></tr> | ||
[[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4luq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4luq OCA], [https://pdbe.org/4luq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4luq RCSB], [https://www.ebi.ac.uk/pdbsum/4luq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4luq ProSAT]</span></td></tr> | ||
[ | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/TSE3_PSEAE TSE3_PSEAE] Toxin secreted by the H1 type VI (H1-T6SS) secretion system into the periplasm of recipient cells. Degrades peptidoglycan via muramidase activity thereby helping itself to compete with other bacteria (PubMed:21776080). To protect itself, the bacterium synthesizes immunity protein Tsi3 that specifically interacts with and inactivates cognate toxin (PubMed:24025333).<ref>PMID:21776080</ref> <ref>PMID:24025333</ref> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pseudomonas aeruginosa PAO1]] | |||
[[Category: Li L]] | |||
[[Category: Wang T]] | |||
[[Category: Zhang W]] | |||
Latest revision as of 08:55, 20 March 2024
Crystal structure of virulence effector Tse3 in complex with neutralizer Tsi3
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