4msu: Difference between revisions

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New page: '''Unreleased structure''' The entry 4msu is ON HOLD Authors: Ashton, K. S., Andrews, K. L., Bryan, M. C., Chen, J., Chen, K., Chen, M., Chmait, S., Croghan, M., Cupples, R., Fotsch, C....
 
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'''Unreleased structure'''


The entry 4msu is ON HOLD
==Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate==
<StructureSection load='4msu' size='340' side='right'caption='[[4msu]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4msu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MSU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MSU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2EU:1,1,1,3,3,3-HEXAFLUORO-2-{4-[4-(THIOPHEN-2-YLSULFONYL)PIPERAZIN-1-YL]PHENYL}PROPAN-2-OL'>2EU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4msu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4msu OCA], [https://pdbe.org/4msu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4msu RCSB], [https://www.ebi.ac.uk/pdbsum/4msu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4msu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GCKR_HUMAN GCKR_HUMAN] Inhibits glucokinase by forming an inactive complex with this enzyme.


Authors: Ashton, K. S., Andrews, K. L., Bryan, M. C., Chen, J., Chen, K., Chen, M., Chmait, S., Croghan, M., Cupples, R., Fotsch, C., Helmering, J., Jordan, S. R., Kurzeja, R. J., Michelsen, K., Pennington, L. D., Poon, S. F., Sivits, G., Van, G., Vonderfecht, S. L., Wahl, R. C., Zhang, J., Lloyd, D. J., Hale, C., St. Jean, D. J.
==See Also==
 
*[[Glucokinase Regulatory Protein|Glucokinase Regulatory Protein]]
Description: Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Andrews KL]]
[[Category: Ashton KS]]
[[Category: Bryan MC]]
[[Category: Chen J]]
[[Category: Chen K]]
[[Category: Chen M]]
[[Category: Chmait S]]
[[Category: Croghan M]]
[[Category: Cupples R]]
[[Category: Fotsch C]]
[[Category: Hale C]]
[[Category: Helmering J]]
[[Category: Jordan SR]]
[[Category: Kurzeja RJ]]
[[Category: Lloyd DJ]]
[[Category: Michelsen K]]
[[Category: Pennington LD]]
[[Category: Poon SF]]
[[Category: Sivits G]]
[[Category: St Jean DJ]]
[[Category: Van G]]
[[Category: Vonderfecht SL]]
[[Category: Wahl RC]]
[[Category: Zhang J]]
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