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{{STRUCTURE_4fx7|  PDB=4fx7  |  SCENE=  }}
===Structure of Sym2 D9V+D55V+D130V+D176V===


==Function==
==Structure of Sym2 D9V+D55V+D130V+D176V==
[[http://www.uniprot.org/uniprot/HIS6_THEMA HIS6_THEMA]] IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.[HAMAP-Rule:MF_01013]  
<StructureSection load='4fx7' size='340' side='right'caption='[[4fx7]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4fx7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FX7 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.076&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PI:HYDROGENPHOSPHATE+ION'>PI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fx7 OCA], [https://pdbe.org/4fx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fx7 RCSB], [https://www.ebi.ac.uk/pdbsum/4fx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fx7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HIS6_THEMA HIS6_THEMA] IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.[HAMAP-Rule:MF_01013]


==About this Structure==
==See Also==
[[4fx7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FX7 OCA].
*[[IGPS 3D structures|IGPS 3D structures]]
[[Category: Thermotoga maritima msb8]]
__TOC__
[[Category: Rajendran, C.]]
</StructureSection>
[[Category: Sperl , J M.]]
[[Category: Large Structures]]
[[Category: Sterner, R.]]
[[Category: Thermotoga maritima MSB8]]
[[Category: De novo protein]]
[[Category: Rajendran C]]
[[Category: Fusion protein]]
[[Category: Sperl JM]]
[[Category: Lyase]]
[[Category: Sterner R]]
[[Category: Tim barrel]]

Latest revision as of 11:23, 1 March 2024

Structure of Sym2 D9V+D55V+D130V+D176V

4fx7, resolution 2.08Å

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