2mdp: Difference between revisions

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'''Unreleased structure'''


The entry 2mdp is ON HOLD  until Paper Publication
==The bacteriophage T7 encoded inhibitor (gp1.2) of E. coli dGTP triphosphohydrolase==
 
<StructureSection load='2mdp' size='340' side='right'caption='[[2mdp]]' scene=''>
Authors: Mueller, G.A., London, R.E.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2mdp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_T7 Escherichia phage T7]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MDP FirstGlance]. <br>
Description: The bacteriophage T7 encoded inhibitor (gp1.2) of E. coli dGTP triphosphohydrolase
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdp OCA], [https://pdbe.org/2mdp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mdp RCSB], [https://www.ebi.ac.uk/pdbsum/2mdp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GP12_BPT7 GP12_BPT7] Plays a role in increasing the intracellular pool of dGTP. Interacts with and inhibits host dGTPase/dgt. The complex made of the host dGTPase and gene 1.2 protein creates a GTP-binding site of high affinity. Subsequent binding of GTP to the enzyme-inhibitor complex inhibits its dissociation.<ref>PMID:2155228</ref> <ref>PMID:3549718</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia phage T7]]
[[Category: Large Structures]]
[[Category: London RE]]
[[Category: Mueller GA]]
Retrieved from "https://proteopedia.org/2mdp"