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[[Image:2otd.gif|left|200px]]<br /><applet load="2otd" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2otd, resolution 2.60&Aring;" />
'''The crystal structure of the glycerophosphodiester phosphodiesterase from Shigella flexneri 2a'''<br />


==About this Structure==
==The crystal structure of the glycerophosphodiester phosphodiesterase from Shigella flexneri 2a==
2OTD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri] with <scene name='pdbligand=PO4:'>PO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Phosphodiesterase_I Phosphodiesterase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.1 3.1.4.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OTD OCA].  
<StructureSection load='2otd' size='340' side='right'caption='[[2otd]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
[[Category: Phosphodiesterase I]]
== Structural highlights ==
<table><tr><td colspan='2'>[[2otd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OTD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OTD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2otd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2otd OCA], [https://pdbe.org/2otd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2otd RCSB], [https://www.ebi.ac.uk/pdbsum/2otd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2otd ProSAT], [https://www.topsan.org/Proteins/MCSG/2otd TOPSAN]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ot/2otd_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2otd ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Shigella flexneri]]
[[Category: Shigella flexneri]]
[[Category: Single protein]]
[[Category: Clancy S]]
[[Category: Clancy, S.]]
[[Category: Jiang S]]
[[Category: Jiang, S.]]
[[Category: Joachimiak A]]
[[Category: Joachimiak, A.]]
[[Category: Wu R]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Zhang R]]
[[Category: Wu, R.]]
[[Category: Zhang, R.]]
[[Category: PO4]]
[[Category: glycerophosphodiester phosphodiesterase]]
[[Category: mcsg]]
[[Category: midwest center for structural genomics]]
[[Category: protein structure initiative]]
[[Category: psi-2]]
[[Category: structural genomics]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:22:16 2008''

Latest revision as of 01:17, 21 November 2024

The crystal structure of the glycerophosphodiester phosphodiesterase from Shigella flexneri 2a

2otd, resolution 2.60Å

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