4myx: Difference between revisions
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New page: '''Unreleased structure''' The entry 4myx is ON HOLD Authors: Kim, Y., Makowska-Grzyska, M., Gu, M., Anderson, W.F., Joachimiak, A., Csgid, Center for Structural Genomics of Infectious ... |
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==Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Bacillus anthracis str. Ame complexed with P32== | |||
<StructureSection load='4myx' size='340' side='right'caption='[[4myx]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4myx]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._Ames Bacillus anthracis str. Ames]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MYX FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.701Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2F0:2-CHLORO-5-{[(2-{3-[(1E)-N-HYDROXYETHANIMIDOYL]PHENYL}PROPAN-2-YL)CARBAMOYL]AMINO}BENZAMIDE'>2F0</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4myx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4myx OCA], [https://pdbe.org/4myx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4myx RCSB], [https://www.ebi.ac.uk/pdbsum/4myx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4myx ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A6L8P2U9_BACAN A0A6L8P2U9_BACAN] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964] | |||
==See Also== | |||
*[[Inosine monophosphate dehydrogenase 3D structures|Inosine monophosphate dehydrogenase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bacillus anthracis str. Ames]] | |||
[[Category: Large Structures]] | |||
[[Category: Anderson WF]] | |||
[[Category: CSGID]] | |||
[[Category: Gorla SK]] | |||
[[Category: Gu M]] | |||
[[Category: Hedstrom L]] | |||
[[Category: Joachimiak A]] | |||
[[Category: Kim Y]] | |||
[[Category: Makowska-Grzyska M]] | |||
Latest revision as of 16:44, 20 September 2023
Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Bacillus anthracis str. Ame complexed with P32
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