4j5l: Difference between revisions
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== | ==Structure of the Cargo Binding Domain from Human Myosin Va== | ||
[[http://www.uniprot.org/uniprot/MYO5A_HUMAN MYO5A_HUMAN | <StructureSection load='4j5l' size='340' side='right'caption='[[4j5l]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4j5l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J5L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J5L FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j5l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j5l OCA], [https://pdbe.org/4j5l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j5l RCSB], [https://www.ebi.ac.uk/pdbsum/4j5l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j5l ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/MYO5A_HUMAN MYO5A_HUMAN] Griscelli disease type 3;Neuroectodermal melanolysosomal disease;Griscelli disease type 1. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MYO5A_HUMAN MYO5A_HUMAN] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.<ref>PMID:10448864</ref> | |||
== | ==See Also== | ||
*[[Myosin 3D Structures|Myosin 3D Structures]] | |||
== References == | |||
<references/> | |||
[[ | __TOC__ | ||
</StructureSection> | |||
== | |||
<references | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Assis | [[Category: Large Structures]] | ||
[[Category: Berridge | [[Category: Assis LHP]] | ||
[[Category: Burgess-Brown | [[Category: Berridge G]] | ||
[[Category: Burgess-Brown N]] | |||
[[Category: Krojer | [[Category: Krojer T]] | ||
[[Category: Mahajan | [[Category: Mahajan P]] | ||
[[Category: Murakami | [[Category: Murakami MT]] | ||
[[Category: Nascimento | [[Category: Nascimento AFZ]] | ||
[[Category: Tonoli | [[Category: Tonoli CCC]] | ||
[[Category: Trindade | [[Category: Trindade DM]] | ||
[[Category: Vollmar | [[Category: Vollmar M]] | ||
[[Category: | [[Category: Von Delft F]] | ||
Latest revision as of 12:01, 1 March 2024
Structure of the Cargo Binding Domain from Human Myosin Va
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