4n5u: Difference between revisions
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New page: '''Unreleased structure''' The entry 4n5u is ON HOLD Authors: Kumar, P.R., Banu, R., Bhosle, R., Calarese, D.A., Celikgil, A., Chamala, S., Chan, M.K., Chowdhury, S., Fiser, A., Garfort... |
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==Crystal structure of the 4th FN3 domain of human Protein Tyrosine phosphatase, receptor type F [PSI-NYSGRC-006240]== | |||
<StructureSection load='4n5u' size='340' side='right'caption='[[4n5u]], [[Resolution|resolution]] 1.46Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4n5u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N5U FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.456Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n5u OCA], [https://pdbe.org/4n5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n5u RCSB], [https://www.ebi.ac.uk/pdbsum/4n5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n5u ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PTPRF_HUMAN PTPRF_HUMAN] Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase).<ref>PMID:10338209</ref> The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.<ref>PMID:10338209</ref> | |||
==See Also== | |||
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Almo SC]] | |||
[[Category: Attonito J]] | |||
[[Category: Banu R]] | |||
[[Category: Bhosle R]] | |||
[[Category: Calarese DA]] | |||
[[Category: Casadevall A]] | |||
[[Category: Celikgil A]] | |||
[[Category: Chamala S]] | |||
[[Category: Chan MK]] | |||
[[Category: Chowdhury S]] | |||
[[Category: Fiser A]] | |||
[[Category: Garforth SJ]] | |||
[[Category: Glenn AS]] | |||
[[Category: Hillerich B]] | |||
[[Category: Khafizov K]] | |||
[[Category: Kumar PR]] | |||
[[Category: Love JD]] | |||
[[Category: Patel H]] | |||
[[Category: Patel R]] | |||
[[Category: Seidel RD]] | |||
[[Category: Smith B]] | |||
[[Category: Stead M]] | |||
[[Category: Toro R]] | |||
Latest revision as of 16:48, 20 September 2023
Crystal structure of the 4th FN3 domain of human Protein Tyrosine phosphatase, receptor type F [PSI-NYSGRC-006240]
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