4k34: Difference between revisions

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{{STRUCTURE_4k34|  PDB=4k34  |  SCENE=  }}
===Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation===
{{ABSTRACT_PUBMED_24099674}}


==About this Structure==
==Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation==
[[4k34]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K34 OCA].  
<StructureSection load='4k34' size='340' side='right'caption='[[4k34]], [[Resolution|resolution]] 2.69&Aring;' scene=''>
 
== Structural highlights ==
==Reference==
<table><tr><td colspan='2'>[[4k34]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K34 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K34 FirstGlance]. <br>
<ref group="xtra">PMID:024099674</ref><references group="xtra"/><references/>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.69&#8491;</td></tr>
[[Category: Escherichia coli k-12]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k34 OCA], [https://pdbe.org/4k34 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k34 RCSB], [https://www.ebi.ac.uk/pdbsum/4k34 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k34 ProSAT]</span></td></tr>
[[Category: Su, C C.]]
</table>
[[Category: Beta barrel]]
== Function ==
[[Category: Membrane protein]]
[https://www.uniprot.org/uniprot/CUSC_ECOLI CUSC_ECOLI] Part of a cation efflux system that mediates resistance to copper and silver. In pathogenic strains it allows the bacteria to invade brain microvascular endothelial cells (BMEC) thus allowing it to cross the blood-brain barrier and cause neonatal meningitis.<ref>PMID:11399769</ref> <ref>PMID:12813074</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Su C-C]]

Latest revision as of 12:08, 1 March 2024

Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation

4k34, resolution 2.69Å

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