4k7k: Difference between revisions

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{{STRUCTURE_4k7k|  PDB=4k7k  |  SCENE=  }}
===Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation===
{{ABSTRACT_PUBMED_24099674}}


==About this Structure==
==Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation==
[[4k7k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K7K OCA].  
<StructureSection load='4k7k' size='340' side='right'caption='[[4k7k]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
 
== Structural highlights ==
==Reference==
<table><tr><td colspan='2'>[[4k7k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K7K FirstGlance]. <br>
<ref group="xtra">PMID:024099674</ref><references group="xtra"/><references/>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.53&#8491;</td></tr>
[[Category: Escherichia coli k-12]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k7k OCA], [https://pdbe.org/4k7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k7k RCSB], [https://www.ebi.ac.uk/pdbsum/4k7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k7k ProSAT]</span></td></tr>
[[Category: Lei, H T.]]
</table>
[[Category: Su, C C.]]
== Function ==
[[Category: Beta barrel]]
[https://www.uniprot.org/uniprot/CUSC_ECOLI CUSC_ECOLI] Part of a cation efflux system that mediates resistance to copper and silver. In pathogenic strains it allows the bacteria to invade brain microvascular endothelial cells (BMEC) thus allowing it to cross the blood-brain barrier and cause neonatal meningitis.<ref>PMID:11399769</ref> <ref>PMID:12813074</ref>
[[Category: Membrane protein]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Lei H-T]]
[[Category: Su C-C]]