4n7u: Difference between revisions
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New page: '''Unreleased structure''' The entry 4n7u is ON HOLD Authors: Sandstrom, A., Adams, E.J. Description: Crystal Structure of Intracellular B30.2 Domain of BTN3A1 in Complex with CHDMAPP |
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==Crystal Structure of Intracellular B30.2 Domain of BTN3A1 in Complex with CHDMAPP== | |||
<StructureSection load='4n7u' size='340' side='right'caption='[[4n7u]], [[Resolution|resolution]] 1.46Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4n7u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N7U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N7U FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4598Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2JA:[(E)-4-METHYL-5-OXIDANYL-PENT-3-ENYL]-PHOSPHONOOXY-PHOSPHINIC+ACID'>2JA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n7u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n7u OCA], [https://pdbe.org/4n7u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n7u RCSB], [https://www.ebi.ac.uk/pdbsum/4n7u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n7u ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BT3A1_HUMAN BT3A1_HUMAN] Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.<ref>PMID:21113407</ref> <ref>PMID:21918970</ref> <ref>PMID:22767497</ref> <ref>PMID:22846996</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Adams EJ]] | |||
[[Category: Sandstrom A]] | |||