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[[Image:2pcq.jpg|left|200px]]<br /><applet load="2pcq" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2pcq, resolution 2.10&Aring;" />
'''Crystal structure of putative dihidrodipicolinate synthase (TTHA0737) from Thermus Thermophilus HB8'''<br />


==About this Structure==
==Crystal structure of putative dihydrodipicolinate synthase (TTHA0737) from Thermus Thermophilus HB8==
2PCQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=K:'>K</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydrodipicolinate_synthase Dihydrodipicolinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.52 4.2.1.52] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PCQ OCA].  
<StructureSection load='2pcq' size='340' side='right'caption='[[2pcq]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
[[Category: Dihydrodipicolinate synthase]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2pcq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PCQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PCQ FirstGlance]. <br>
[[Category: Thermus thermophilus]]
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
[[Category: Ebihara, A.]]
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
[[Category: Jeyakanthan, J.]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/4-hydroxy-tetrahydrodipicolinate_synthase 4-hydroxy-tetrahydrodipicolinate synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.3.7 4.3.3.7] </span></td></tr>
[[Category: Kanaujia, S P.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pcq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pcq OCA], [https://pdbe.org/2pcq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pcq RCSB], [https://www.ebi.ac.uk/pdbsum/2pcq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pcq ProSAT], [https://www.topsan.org/Proteins/RSGI/2pcq TOPSAN]</span></td></tr>
[[Category: Kitamura, Y.]]
</table>
[[Category: Kuramitsu, S.]]
== Evolutionary Conservation ==
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Ranjani, C Vasuki.]]
Check<jmol>
[[Category: Sekar, K.]]
  <jmolCheckbox>
[[Category: Shinkai, A.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pc/2pcq_consurf.spt"</scriptWhenChecked>
[[Category: Shiro, Y.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Yokoyama, S.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: GOL]]
  </jmolCheckbox>
[[Category: K]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pcq ConSurf].
[[Category: dihydrodipicoliante]]
<div style="clear:both"></div>
[[Category: lyase]]
__TOC__
[[Category: lysine biosynthesis]]
</StructureSection>
[[Category: national project on protein structural and functional analyses]]
[[Category: 4-hydroxy-tetrahydrodipicolinate synthase]]
[[Category: nppsfa]]
[[Category: Large Structures]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: Thet8]]
[[Category: rsgi]]
[[Category: Ebihara, A]]
[[Category: structural genomics]]
[[Category: Jeyakanthan, J]]
[[Category: synthase]]
[[Category: Kanaujia, S P]]
 
[[Category: Kitamura, Y]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:28:15 2008''
[[Category: Kuramitsu, S]]
[[Category: Structural genomic]]
[[Category: Ranjani, C Vasuki]]
[[Category: Sekar, K]]
[[Category: Shinkai, A]]
[[Category: Shiro, Y]]
[[Category: Yokoyama, S]]
[[Category: Dihydrodipicoliante]]
[[Category: Lyase]]
[[Category: Lysine biosynthesis]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rsgi]]
[[Category: Synthase]]