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[[Image:2pcr.jpg|left|200px]]<br /><applet load="2pcr" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2pcr, resolution 2.60&Aring;" />
'''Crystal structure of Myo-inositol-1(or 4)-monophosphatase (aq_1983) from Aquifex Aeolicus VF5'''<br />


==About this Structure==
==Crystal structure of Myo-inositol-1(or 4)-monophosphatase (aq_1983) from Aquifex Aeolicus VF5==
2PCR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Active as [http://en.wikipedia.org/wiki/Inositol-phosphate_phosphatase Inositol-phosphate phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.25 3.1.3.25] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PCR OCA].  
<StructureSection load='2pcr' size='340' side='right'caption='[[2pcr]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
[[Category: Aquifex aeolicus]]
== Structural highlights ==
[[Category: Inositol-phosphate phosphatase]]
<table><tr><td colspan='2'>[[2pcr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PCR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PCR FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
[[Category: Agari, Y.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
[[Category: Antonyuk, S V.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pcr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pcr OCA], [https://pdbe.org/2pcr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pcr RCSB], [https://www.ebi.ac.uk/pdbsum/2pcr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pcr ProSAT], [https://www.topsan.org/Proteins/RSGI/2pcr TOPSAN]</span></td></tr>
[[Category: Bessho, Y.]]
</table>
[[Category: Ebihara, A.]]
== Function ==
[[Category: Ellis, M J.]]
[https://www.uniprot.org/uniprot/BSUHB_AQUAE BSUHB_AQUAE] Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, and both D and L isomers of inositol-1-phosphate (I-1-P).
[[Category: Gayathri, D.]]
== Evolutionary Conservation ==
[[Category: Hasnain, S S.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Jeyakanthan, J.]]
Check<jmol>
[[Category: Kuramitsu, S.]]
  <jmolCheckbox>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pc/2pcr_consurf.spt"</scriptWhenChecked>
[[Category: Shinkai, A.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Shiro, Y.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Strange, R W.]]
  </jmolCheckbox>
[[Category: Velmurugan, D.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pcr ConSurf].
[[Category: Yokoyama, S.]]
<div style="clear:both"></div>
[[Category: bipolar disorder]]
[[Category: hydrolase]]
[[Category: myo-inositol monophosphatase(impa)]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:28:23 2008''
==See Also==
*[[Inositol monophosphatase 3D structures|Inositol monophosphatase 3D structures]]
__TOC__
</StructureSection>
[[Category: Aquifex aeolicus VF5]]
[[Category: Large Structures]]
[[Category: Agari Y]]
[[Category: Antonyuk SV]]
[[Category: Bessho Y]]
[[Category: Ebihara A]]
[[Category: Ellis MJ]]
[[Category: Gayathri D]]
[[Category: Hasnain SS]]
[[Category: Jeyakanthan J]]
[[Category: Kuramitsu S]]
[[Category: Shinkai A]]
[[Category: Shiro Y]]
[[Category: Strange RW]]
[[Category: Velmurugan D]]
[[Category: Yokoyama S]]
Retrieved from "https://proteopedia.org/2pcr"