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{{STRUCTURE_1mg5|  PDB=1mg5  |  SCENE=  }}
===Crystal structure of Drosophila melanogaster alcohol dehydrogenase complexed with NADH and acetate at 1.6 A===
{{ABSTRACT_PUBMED_15581900}}


==About this Structure==
==Crystal structure of Drosophila melanogaster alcohol dehydrogenase complexed with NADH and acetate at 1.6 A==
[[1mg5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MG5 OCA].  
<StructureSection load='1mg5' size='340' side='right'caption='[[1mg5]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1mg5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MG5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MG5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.63&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mg5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mg5 OCA], [https://pdbe.org/1mg5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mg5 RCSB], [https://www.ebi.ac.uk/pdbsum/1mg5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mg5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ADH_DROME ADH_DROME]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mg/1mg5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mg5 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Alcohol dehydrogenase|Alcohol dehydrogenase]]
*[[Alcohol dehydrogenase 3D structures|Alcohol dehydrogenase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:015581900</ref><references group="xtra"/><references/>
[[Category: Alcohol dehydrogenase]]
[[Category: Drosophila melanogaster]]
[[Category: Atrian, S.]]
[[Category: Benach, J.]]
[[Category: Gonzalez-Duarte, R.]]
[[Category: Ladenstein, R.]]
[[Category: Acetate]]
[[Category: Adh]]
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Nadh]]
[[Category: Large Structures]]
[[Category: Oxidoreductase]]
[[Category: Atrian S]]
[[Category: Sdr]]
[[Category: Benach J]]
[[Category: Gonzalez-Duarte R]]
[[Category: Ladenstein R]]
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