2poy: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| (13 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
== | ==Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_4120 in complex with cyclosporin A== | ||
<StructureSection load='2poy' size='340' side='right'caption='[[2poy]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
[[ | == Structural highlights == | ||
[[ | <table><tr><td colspan='2'>[[2poy]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II] and [https://en.wikipedia.org/wiki/Tolypocladium_inflatum Tolypocladium inflatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2POY FirstGlance]. <br> | ||
[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
[[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr> | ||
[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2poy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2poy OCA], [https://pdbe.org/2poy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2poy RCSB], [https://www.ebi.ac.uk/pdbsum/2poy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2poy ProSAT]</span></td></tr> | ||
[[ | </table> | ||
[ | == Function == | ||
[ | [https://www.uniprot.org/uniprot/A3FQA7_CRYPI A3FQA7_CRYPI] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.[RuleBase:RU004223] | ||
[[Category: | == Evolutionary Conservation == | ||
[[Category: | [[Image:Consurf_key_small.gif|200px|right]] | ||
[[Category: | Check<jmol> | ||
[[Category: | <jmolCheckbox> | ||
[[Category: | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/po/2poy_consurf.spt"</scriptWhenChecked> | ||
[[Category: | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
[[Category: | <text>to colour the structure by Evolutionary Conservation</text> | ||
[[Category: | </jmolCheckbox> | ||
[[Category: | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2poy ConSurf]. | ||
[[Category: | <div style="clear:both"></div> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Cryptosporidium parvum Iowa II]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Tolypocladium inflatum]] | ||
[[Category: | [[Category: Arrowsmith CH]] | ||
[[Category: | [[Category: Artz JD]] | ||
[[Category: | [[Category: Bochkarev A]] | ||
[[Category: Edwards AM]] | |||
[[Category: Hassanali A]] | |||
[[Category: Hills T]] | |||
[[Category: Hui R]] | |||
[[Category: Kozieradzki I]] | |||
[[Category: Lew J]] | |||
[[Category: Lin YH]] | |||
[[Category: Schapira M]] | |||
[[Category: Sundstrom M]] | |||
[[Category: Weigelt J]] | |||
[[Category: Wernimont AK]] | |||
[[Category: Xiao T]] | |||
[[Category: Zhao Y]] | |||
Latest revision as of 11:06, 30 August 2023
Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_4120 in complex with cyclosporin A
| ||||||||||||
