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{{STRUCTURE_4khz|  PDB=4khz  |  SCENE=  }}
===Crystal structure of the maltose-binding protein/maltose transporter complex in an pre-translocation conformation bound to maltoheptaose===
{{ABSTRACT_PUBMED_24145421}}


==Function==
==Crystal structure of the maltose-binding protein/maltose transporter complex in an pre-translocation conformation bound to maltoheptaose==
[[http://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI]] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides. [[http://www.uniprot.org/uniprot/MALF_ECOLI MALF_ECOLI]] Part of the binding-protein-dependent transport system for maltose; probably responsible for the translocation of the substrate across the membrane.  
<StructureSection load='4khz' size='340' side='right'caption='[[4khz]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4khz]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_DH1 Escherichia coli DH1] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KHZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PGV:(1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL+(11E)-OCTADEC-11-ENOATE'>PGV</scene>, <scene name='pdbligand=PRD_900009:alpha-maltotriose'>PRD_900009</scene>, <scene name='pdbligand=PRD_900010:alpha-maltotetraose'>PRD_900010</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4khz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4khz OCA], [https://pdbe.org/4khz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4khz RCSB], [https://www.ebi.ac.uk/pdbsum/4khz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4khz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.


==About this Structure==
==See Also==
[[4khz]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_dh1 Escherichia coli dh1] and [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHZ OCA].
*[[Maltose-binding protein 3D structures|Maltose-binding protein 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:024145421</ref><references group="xtra"/><references/>
[[Category: Escherichia coli DH1]]
[[Category: Escherichia coli dh1]]
[[Category: Escherichia coli K-12]]
[[Category: Escherichia coli k-12]]
[[Category: Large Structures]]
[[Category: Chen, J.]]
[[Category: Chen J]]
[[Category: Chen, S.]]
[[Category: Chen S]]
[[Category: Oldham, M L.]]
[[Category: Oldham ML]]
[[Category: Abc transporter]]
[[Category: Atp binding maltodextrin binding]]
[[Category: Atpase maltodextrin transporter]]
[[Category: Inner membrane]]
[[Category: Transport protein]]
Retrieved from "https://proteopedia.org/4khz"