4nac: Difference between revisions
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New page: '''Unreleased structure''' The entry 4nac is ON HOLD Authors: Mei, K., Jin, Z., Ren, F., Wang, Y. Description: Crystal Structure of the N-terminal Domain of p15RS |
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==Crystal Structure of the N-terminal Domain of p15RS== | |||
<StructureSection load='4nac' size='340' side='right'caption='[[4nac]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4nac]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NAC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NAC FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.002Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nac OCA], [https://pdbe.org/4nac PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nac RCSB], [https://www.ebi.ac.uk/pdbsum/4nac PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nac ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RPR1A_HUMAN RPR1A_HUMAN] Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.<ref>PMID:12470661</ref> <ref>PMID:22231121</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Jin Z]] | |||
[[Category: Mei K]] | |||
[[Category: Ren F]] | |||
[[Category: Wang Y]] | |||
Latest revision as of 08:56, 20 March 2024
Crystal Structure of the N-terminal Domain of p15RS
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