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[[Image:2pwz.jpg|left|200px]]<br /><applet load="2pwz" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2pwz, resolution 2.200&Aring;" />
'''Crystal structure of the apo form of E.Coli malate dehydrogenase'''<br />


==About this Structure==
==Crystal structure of the apo form of E.Coli malate dehydrogenase==
2PWZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Active as [http://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWZ OCA].  
<StructureSection load='2pwz' size='340' side='right'caption='[[2pwz]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
[[Category: Escherichia coli]]
== Structural highlights ==
[[Category: Malate dehydrogenase]]
<table><tr><td colspan='2'>[[2pwz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PWZ FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
[[Category: Clarke, T A.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pwz OCA], [https://pdbe.org/2pwz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pwz RCSB], [https://www.ebi.ac.uk/pdbsum/2pwz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pwz ProSAT]</span></td></tr>
[[Category: Hemmings, A M.]]
</table>
[[Category: Richardson, D J.]]
== Function ==
[[Category: Soderberg, C A.G.]]
[https://www.uniprot.org/uniprot/MDH_ECOLI MDH_ECOLI] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_01516]
[[Category: apo form of e coli malate dehydrogenase in space group c2]]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pw/2pwz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pwz ConSurf].
<div style="clear:both"></div>


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:33:48 2008''
==See Also==
*[[Malate Dehydrogenase 3D structures|Malate Dehydrogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Clarke TA]]
[[Category: Hemmings AM]]
[[Category: Richardson DJ]]
[[Category: Soderberg CAG]]

Latest revision as of 11:11, 30 August 2023

Crystal structure of the apo form of E.Coli malate dehydrogenase

2pwz, resolution 2.20Å

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