4m1m: Difference between revisions

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{{STRUCTURE_4m1m|  PDB=4m1m  |  SCENE=  }}
===Corrected Structure of Mouse P-glycoprotein===
{{ABSTRACT_PUBMED_24155053}}


==Function==
==Corrected Structure of Mouse P-glycoprotein==
[[http://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE]] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref> 
<StructureSection load='4m1m' size='340' side='right'caption='[[4m1m]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4m1m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M1M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M1M FirstGlance]. <br>
[[4m1m]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M1M OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m1m OCA], [https://pdbe.org/4m1m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m1m RCSB], [https://www.ebi.ac.uk/pdbsum/4m1m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m1m ProSAT]</span></td></tr>
<ref group="xtra">PMID:024155053</ref><references group="xtra"/><references/>
</table>
[[Category: Xenobiotic-transporting ATPase]]
== Function ==
[[Category: Aller, S G.]]
[https://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref>
[[Category: Jaimes, K F.]]
== References ==
[[Category: Li, J.]]
<references/>
[[Category: Adenosine triphosphate]]
__TOC__
[[Category: Atp-binding cassette transporter]]
</StructureSection>
[[Category: Hydrolase]]
[[Category: Large Structures]]
[[Category: Mercurated cysteine]]
[[Category: Mus musculus]]
[[Category: Multidrug efflux]]
[[Category: Aller SG]]
[[Category: Plasma membrane]]
[[Category: Jaimes KF]]
[[Category: Li J]]

Latest revision as of 12:23, 1 March 2024

Corrected Structure of Mouse P-glycoprotein

4m1m, resolution 3.80Å

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