4nf2: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
New page: {{STRUCTURE_4nf2| PDB=4nf2 | SCENE= }} ===Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline=== ...
 
OCA (talk | contribs)
No edit summary
 
(5 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{STRUCTURE_4nf2|  PDB=4nf2  |  SCENE=  }}
===Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline===


==Function==
==Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline==
[[http://www.uniprot.org/uniprot/OTC_BACAN OTC_BACAN]] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).[HAMAP-Rule:MF_01109]  
<StructureSection load='4nf2' size='340' side='right'caption='[[4nf2]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4nf2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._'Ames_Ancestor' Bacillus anthracis str. 'Ames Ancestor']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NF2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CP:PHOSPHORIC+ACID+MONO(FORMAMIDE)ESTER'>CP</scene>, <scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nf2 OCA], [https://pdbe.org/4nf2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nf2 RCSB], [https://www.ebi.ac.uk/pdbsum/4nf2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nf2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OTC_BACAN OTC_BACAN] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).[HAMAP-Rule:MF_01109]


==About this Structure==
==See Also==
[[4nf2]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NF2 OCA].
*[[Ornithine carbamoyltransferase 3D structures|Ornithine carbamoyltransferase 3D structures]]
[[Category: Ornithine carbamoyltransferase]]
__TOC__
[[Category: Anderson, W F.]]
</StructureSection>
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Bacillus anthracis str. 'Ames Ancestor']]
[[Category: Cymborowski, M T.]]
[[Category: Large Structures]]
[[Category: Handing, K.]]
[[Category: Anderson WF]]
[[Category: Minor, W.]]
[[Category: Cymborowski MT]]
[[Category: Shabalin, I G.]]
[[Category: Handing K]]
[[Category: Shuvalova, L.]]
[[Category: Minor W]]
[[Category: Stam, J.]]
[[Category: Shabalin IG]]
[[Category: Winsor, J.]]
[[Category: Shuvalova L]]
[[Category: Carbamoyl phosphate]]
[[Category: Stam J]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Winsor J]]
[[Category: Csgid]]
[[Category: L-ornithine]]
[[Category: National institute of allergy and infectious disease]]
[[Category: Niaid]]
[[Category: Structural genomic]]
[[Category: Transferase]]

Latest revision as of 16:55, 20 September 2023

Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline

4nf2, resolution 1.74Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA