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{{STRUCTURE_4kea|  PDB=4kea  |  SCENE=  }}
===Crystal structure of D196N mutant of Monoglyceride lipase from Bacillus sp. H257 in space group P212121===
{{ABSTRACT_PUBMED_24014019}}


==Function==
==Crystal structure of D196N mutant of Monoglyceride lipase from Bacillus sp. H257 in space group P212121==
[[http://www.uniprot.org/uniprot/MGLP_BAC25 MGLP_BAC25]] Hydrolyzes monoacylglycerols, with the highest activity occurring with 1-monolauroylglycerol.  
<StructureSection load='4kea' size='340' side='right'caption='[[4kea]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4kea]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._H-257 Bacillus sp. H-257]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KEA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kea OCA], [https://pdbe.org/4kea PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kea RCSB], [https://www.ebi.ac.uk/pdbsum/4kea PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kea ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MGLP_BAC25 MGLP_BAC25] Hydrolyzes monoacylglycerols, with the highest activity occurring with 1-monolauroylglycerol.


==About this Structure==
==See Also==
[[4kea]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bac25 Bac25]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEA OCA].
*[[Lipase 3D Structures|Lipase 3D Structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:024014019</ref><references group="xtra"/><references/>
[[Category: Bacillus sp. H-257]]
[[Category: Acylglycerol lipase]]
[[Category: Large Structures]]
[[Category: Bac25]]
[[Category: Aschauer P]]
[[Category: Aschauer, P.]]
[[Category: Dreveny I]]
[[Category: Dreveny, I.]]
[[Category: Gruber K]]
[[Category: Gruber, K.]]
[[Category: Oberer M]]
[[Category: Oberer, M.]]
[[Category: Rengachari S]]
[[Category: Rengachari, S.]]
[[Category: Alpha/beta hydrolase]]
[[Category: Hydrolase]]
[[Category: Monoglyceride lipase]]

Latest revision as of 12:11, 1 March 2024

Crystal structure of D196N mutant of Monoglyceride lipase from Bacillus sp. H257 in space group P212121

4kea, resolution 1.70Å

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