3wlu: Difference between revisions
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New page: '''Unreleased structure''' The entry 3wlu is ON HOLD Authors: Makyio, Hisayoshi, Suzuki, Tatsuya, Ando, Hiromune, Yamada, Yusuke, Ishida, Hideharu, Kiso, Makoto, Wakatsuki, Soichi, Kato... |
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==Crystal Structure of human galectin-9 NCRD with Selenolactose== | |||
<StructureSection load='3wlu' size='340' side='right'caption='[[3wlu]], [[Resolution|resolution]] 1.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3wlu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WLU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WLU FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LSE:2-(TRIMETHYLSILYL)ETHYL+4-O-BETA-D-GALACTOPYRANOSYL-6-SE-METHYL-6-SELENO-BETA-D-GLUCOPYRANOSIDE'>LSE</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wlu OCA], [https://pdbe.org/3wlu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wlu RCSB], [https://www.ebi.ac.uk/pdbsum/3wlu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wlu ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/LEG9_HUMAN LEG9_HUMAN] Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant.<ref>PMID:16286920</ref> <ref>PMID:18005988</ref> <ref>PMID:18977853</ref> | |||
==See Also== | |||
*[[Galectin 3D structures|Galectin 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Ando H]] | |||
[[Category: Ishida H]] | |||
[[Category: Kato R]] | |||
[[Category: Kiso M]] | |||
[[Category: Makyio H]] | |||
[[Category: Suzuki T]] | |||
[[Category: Wakatsuki S]] | |||
[[Category: Yamada Y]] | |||
Latest revision as of 08:45, 20 March 2024
Crystal Structure of human galectin-9 NCRD with Selenolactose
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