4nfb: Difference between revisions
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==Structure of paired immunoglobulin-like type 2 receptor (PILR )== | |||
<StructureSection load='4nfb' size='340' side='right'caption='[[4nfb]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4nfb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NFB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NFB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nfb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nfb OCA], [https://pdbe.org/4nfb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nfb RCSB], [https://www.ebi.ac.uk/pdbsum/4nfb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nfb ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PILRA_HUMAN PILRA_HUMAN] Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRA is thought to act as a cellular signaling inhibitory receptor by recruiting cytoplasmic phosphatases like PTPN6/SHP-1 and PTPN11/SHP-2 via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Receptor for PIANP.<ref>PMID:10903717</ref> <ref>PMID:18358807</ref> <ref>PMID:21241660</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Fan Z]] | |||
[[Category: Gao G]] | |||
[[Category: Li Y]] | |||
[[Category: Lu G]] | |||
[[Category: Lu Q]] | |||
[[Category: Qi J]] | |||
[[Category: Wang H]] | |||
[[Category: Yan J]] | |||
[[Category: Zhang Y]] | |||
Latest revision as of 08:56, 20 March 2024
Structure of paired immunoglobulin-like type 2 receptor (PILR )
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