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{{STRUCTURE_3tow|  PDB=3tow  |  SCENE=  }}
===Crystal Structure of the MABP Domain of MVB12B of Human ESCRT-I Complex===
{{ABSTRACT_PUBMED_22232651}}


==Function==
==Crystal Structure of the MABP Domain of MVB12B of Human ESCRT-I Complex==
[[http://www.uniprot.org/uniprot/MB12B_HUMAN MB12B_HUMAN]] Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.  
<StructureSection load='3tow' size='340' side='right'caption='[[3tow]], [[Resolution|resolution]] 1.34&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3tow]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TOW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TOW FirstGlance]. <br>
[[3tow]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TOW OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.34&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tow OCA], [https://pdbe.org/3tow PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tow RCSB], [https://www.ebi.ac.uk/pdbsum/3tow PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tow ProSAT]</span></td></tr>
==Reference==
</table>
<ref group="xtra">PMID:022232651</ref><references group="xtra"/><references/>
== Function ==
[[Category: Human]]
[https://www.uniprot.org/uniprot/MB12B_HUMAN MB12B_HUMAN] Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.
[[Category: Boura, E.]]
__TOC__
[[Category: Hurley, J H.]]
</StructureSection>
[[Category: Beta prism]]
[[Category: Homo sapiens]]
[[Category: Membrane binding domain]]
[[Category: Large Structures]]
[[Category: Negatively charged membrane]]
[[Category: Boura E]]
[[Category: Protein transport]]
[[Category: Hurley JH]]
Retrieved from "https://proteopedia.org/3tow"