2rt9: Difference between revisions
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==Solution structure of a regulatory domain of meiosis inhibitor== | |||
<StructureSection load='2rt9' size='340' side='right'caption='[[2rt9]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2rt9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RT9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rt9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rt9 OCA], [https://pdbe.org/2rt9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rt9 RCSB], [https://www.ebi.ac.uk/pdbsum/2rt9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rt9 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FBX43_MOUSE FBX43_MOUSE] Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Akasaka R]] | |||
[[Category: He F]] | |||
[[Category: Ikeda M]] | |||
[[Category: Muto Y]] | |||
[[Category: Ohsawa N]] | |||
[[Category: Shirouzu M]] | |||
[[Category: Shoji S]] | |||
[[Category: Terada T]] | |||
[[Category: Tsuda K]] | |||
[[Category: Wakiyama M]] | |||
[[Category: Yokoyama S]] | |||
Latest revision as of 07:06, 1 May 2024
Solution structure of a regulatory domain of meiosis inhibitor
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