4nn2: Difference between revisions
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==Protein Crystal Structure of Human Borjeson-Forssman-Lehmann Syndrome Associated Protein PHF6== | |||
<StructureSection load='4nn2' size='340' side='right'caption='[[4nn2]], [[Resolution|resolution]] 1.47Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4nn2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NN2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NN2 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.472Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nn2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nn2 OCA], [https://pdbe.org/4nn2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nn2 RCSB], [https://www.ebi.ac.uk/pdbsum/4nn2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nn2 ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/PHF6_HUMAN PHF6_HUMAN] Borjeson-Forssman-Lehmann syndrome. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PHF6_HUMAN PHF6_HUMAN] Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription.<ref>PMID:23229552</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Li F]] | |||
[[Category: Liu Z]] | |||
[[Category: Mei Y]] | |||
[[Category: Shi Y]] | |||
[[Category: Wu J]] | |||
[[Category: Zhang J]] | |||