4nph: Difference between revisions
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==Crystal structure of SsaN from Salmonella enterica== | |||
<StructureSection load='4nph' size='340' side='right'caption='[[4nph]], [[Resolution|resolution]] 2.09Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4nph]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NPH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NPH FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nph OCA], [https://pdbe.org/4nph PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nph RCSB], [https://www.ebi.ac.uk/pdbsum/4nph PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nph ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SCTN2_SALTY SCTN2_SALTY] ATPase component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:24722491). Acts as a molecular motor to provide the energy that is required for the export of proteins (By similarity). Required for type III secretion apparatus (T3SA) formation, secretion of a subset of SPI-2 effectors and virulence (PubMed:24722491, PubMed:25035427). May play a critical role in T3SS substrate recognition, disassembly of the effector/chaperone complex and unfolding of the effector in an ATP-dependent manner prior to secretion (Probable). Releases the effector protein SseB from the T3SS-2 specific chaperone SsaE in an ATP-dependent manner (PubMed:24722491).[UniProtKB:P0A1B9]<ref>PMID:24722491</ref> <ref>PMID:25035427</ref> <ref>PMID:24722491</ref> <ref>PMID:25035427</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]] | |||
[[Category: Coombes BK]] | |||
[[Category: Cooper CA]] | |||
[[Category: Junop MS]] | |||
[[Category: Sugiman-Marangos SN]] | |||
[[Category: Zhang K]] | |||
Latest revision as of 17:01, 20 September 2023
Crystal structure of SsaN from Salmonella enterica
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