4hhv: Difference between revisions

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{{STRUCTURE_4hhv|  PDB=4hhv  |  SCENE=  }}
===Crystal structure of ceramide transfer protein pleckstrin homology domain===


==Function==
==Crystal structure of ceramide transfer protein pleckstrin homology domain==
[[http://www.uniprot.org/uniprot/C43BP_HUMAN C43BP_HUMAN]] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref>
<StructureSection load='4hhv' size='340' side='right'caption='[[4hhv]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4hhv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HHV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HHV FirstGlance]. <br>
[[4hhv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HHV OCA].
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hhv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hhv OCA], [https://pdbe.org/4hhv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hhv RCSB], [https://www.ebi.ac.uk/pdbsum/4hhv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hhv ProSAT]</span></td></tr>
<references group="xtra"/><references/>
</table>
[[Category: Prashek, J.]]
== Disease ==
[[Category: Truong, T.]]
[https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] The disease is caused by variants affecting the gene represented in this entry.
[[Category: Yao, X.]]
== Function ==
[[Category: Binds to phosphatidylinositol 4-phosphate]]
[https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref>  
[[Category: Lipid transport]]
== References ==
[[Category: Pleckstrin homology domain fold]]
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Prashek J]]
[[Category: Truong T]]
[[Category: Yao X]]
Retrieved from "https://proteopedia.org/4hhv"