4i3t: Difference between revisions
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== | ==Structure of phosphonoacetaldehyde dehydrogenase in the apo state== | ||
[[4i3t]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I3T OCA]. | <StructureSection load='4i3t' size='340' side='right'caption='[[4i3t]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
[[ | == Structural highlights == | ||
[[ | <table><tr><td colspan='2'>[[4i3t]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Sinorhizobium_meliloti_1021 Sinorhizobium meliloti 1021]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I3T FirstGlance]. <br> | ||
[[Category: | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i3t OCA], [https://pdbe.org/4i3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i3t RCSB], [https://www.ebi.ac.uk/pdbsum/4i3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i3t ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PHNY_RHIME PHNY_RHIME] Plays an important role in phosphonate degradation by catalyzing the NAD-dependent conversion of phosphonoacetaldehyde (PnAA) to phosphonoacetate (PnA). Has low in vitro activity with the related compounds phosphonopropionaldehyde (3-oxopropyl phosphonate) and glyceraldehyde 3-phosphate.<ref>PMID:24361046</ref> | |||
==See Also== | |||
*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Sinorhizobium meliloti 1021]] | |||
[[Category: Agarwal V]] | |||
[[Category: Nair SK]] | |||
Latest revision as of 11:49, 1 March 2024
Structure of phosphonoacetaldehyde dehydrogenase in the apo state
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