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[[Image:2qqe.gif|left|200px]]<br /><applet load="2qqe" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2qqe, resolution 1.90&Aring;" />
'''Thymidine Kinase from Thermotoga Maritima in complex with Thymidine'''<br />


==About this Structure==
==Thymidine Kinase from Thermotoga Maritima in complex with Thymidine==
2QQE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=THM:'>THM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thymidine_kinase Thymidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.21 2.7.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QQE OCA].  
<StructureSection load='2qqe' size='340' side='right'caption='[[2qqe]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
[[Category: Single protein]]
== Structural highlights ==
<table><tr><td colspan='2'>[[2qqe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QQE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=THM:THYMIDINE'>THM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qqe OCA], [https://pdbe.org/2qqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qqe RCSB], [https://www.ebi.ac.uk/pdbsum/2qqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qqe ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KITH_THEMA KITH_THEMA]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qq/2qqe_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qqe ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Thymidine kinase 3D structures|Thymidine kinase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
[[Category: Thymidine kinase]]
[[Category: Konrad M]]
[[Category: Konrad, M.]]
[[Category: Lavie A]]
[[Category: Lavie, A.]]
[[Category: Lichter J]]
[[Category: Lichter, J.]]
[[Category: Lutz S]]
[[Category: Lutz, S.]]
[[Category: Segura-Pena D]]
[[Category: Segura-Pena, D.]]
[[Category: Trani M]]
[[Category: Trani, M.]]
[[Category: THM]]
[[Category: ZN]]
[[Category: atp-binding]]
[[Category: close conformation]]
[[Category: cytoplasm]]
[[Category: dna synthesis]]
[[Category: kinase]]
[[Category: nucleotide-binding]]
[[Category: tmtk in complex with thymidine]]
[[Category: transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:41:23 2008''

Latest revision as of 09:17, 21 February 2024

Thymidine Kinase from Thermotoga Maritima in complex with Thymidine

2qqe, resolution 1.90Å

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