2qy7: Difference between revisions
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== | ==Crystal structure of human epsinR ENTH domain== | ||
<StructureSection load='2qy7' size='340' side='right'caption='[[2qy7]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2qy7]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QY7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qy7 OCA], [https://pdbe.org/2qy7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qy7 RCSB], [https://www.ebi.ac.uk/pdbsum/2qy7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qy7 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/EPN4_HUMAN EPN4_HUMAN] Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.<ref>PMID:12429846</ref> <ref>PMID:12538641</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qy/2qy7_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qy7 ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Epsin|Epsin]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Collins | [[Category: Collins BM]] | ||
[[Category: McCoy | [[Category: McCoy AJ]] | ||
[[Category: Miller | [[Category: Miller SE]] | ||
[[Category: Owen | [[Category: Owen DJ]] | ||
[[Category: Robinson | [[Category: Robinson MS]] | ||
Latest revision as of 09:18, 21 February 2024
Crystal structure of human epsinR ENTH domain
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