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{{STRUCTURE_4nob|  PDB=4nob  |  SCENE=  }}
===Crystal structure of the 1st Ig domain from mouse Polymeric Immunoglobulin receptor [PSI-NYSGRC-006220]===


==Function==
==Crystal structure of the 1st Ig domain from mouse Polymeric Immunoglobulin receptor [PSI-NYSGRC-006220]==
[[http://www.uniprot.org/uniprot/PIGR_MOUSE PIGR_MOUSE]] This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment (By similarity).  
<StructureSection load='4nob' size='340' side='right'caption='[[4nob]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4nob]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NOB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NOB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.51&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nob OCA], [https://pdbe.org/4nob PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nob RCSB], [https://www.ebi.ac.uk/pdbsum/4nob PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nob ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PIGR_MOUSE PIGR_MOUSE] This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment (By similarity).


==About this Structure==
==See Also==
[[4nob]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NOB OCA].
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
[[Category: Almo, S C.]]
__TOC__
[[Category: Attonito, J.]]
</StructureSection>
[[Category: Banu, R.]]
[[Category: Large Structures]]
[[Category: Bhosle, R.]]
[[Category: Mus musculus]]
[[Category: Calarese, D A.]]
[[Category: Almo SC]]
[[Category: Casadevall, A.]]
[[Category: Attonito J]]
[[Category: Celikgil, A.]]
[[Category: Banu R]]
[[Category: Chamala, S.]]
[[Category: Bhosle R]]
[[Category: Chan, M K.]]
[[Category: Calarese DA]]
[[Category: Chowdhury, S.]]
[[Category: Casadevall A]]
[[Category: Fiser, A.]]
[[Category: Celikgil A]]
[[Category: Garforth, S J.]]
[[Category: Chamala S]]
[[Category: Glenn, A S.]]
[[Category: Chan MK]]
[[Category: Hillerich, B.]]
[[Category: Chowdhury S]]
[[Category: IFN, Atoms-to-Animals:.The Immune Function Network.]]
[[Category: Fiser A]]
[[Category: Khafizov, K.]]
[[Category: Garforth SJ]]
[[Category: Kumar, P R.]]
[[Category: Glenn AS]]
[[Category: Love, J D.]]
[[Category: Hillerich B]]
[[Category: NYSGRC, New York Structural Genomics Research Consortium.]]
[[Category: Khafizov K]]
[[Category: Patel, H.]]
[[Category: Kumar PR]]
[[Category: Patel, R.]]
[[Category: Love JD]]
[[Category: Seidel, R D.]]
[[Category: Patel H]]
[[Category: Smith, B.]]
[[Category: Patel R]]
[[Category: Stead, M.]]
[[Category: Seidel RD]]
[[Category: Ifn]]
[[Category: Smith B]]
[[Category: Ig domain]]
[[Category: Stead M]]
[[Category: Immune function network]]
[[Category: Immune system]]
[[Category: New york structural genomics research consortium]]
[[Category: Nysgrc]]
[[Category: Ortholog]]
[[Category: Psi-biology]]
[[Category: Structural genomic]]
Retrieved from "https://proteopedia.org/4nob"